The Metrosep Dual 4 columns contain an entirely novel carrier material, namely a functionalized monolith based on silica. This monolith allows flow rates of up to 5 mL/min. Even at such high flow rates the column's counter-pressure remains low. Compared to conventional materials, the monolith with its structure made up of macro- and mesopores has a much larger surface area. This contributes to the high capacity of the Metrosep Dual 4 column, whose dead volume is very low.
The Metrosep Dual 4 – 25 column is short (25 mm) and allows the separation of some standard anions in less than one minute. For example, nitrite and nitrate can be separated in just 45 seconds. This means that ion chromatography is faster than many FIA systems (Flow Injection Analysis systems).
The column can be used with and without chemical suppression. With the standard eluent containing p-cyanophenol the connection of the RP Trap column (6.1014.100) between the pulsation absorber and the injection valve is recommended.