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Titrimetric determination of active pharmaceutical ingredients with the NIO electrode
The NIO electrode is characterized by the fact that it is selective for both sodium tetraphenylborate (= STPB) and oleophilic molecules. This means that it can be used successfully for the potentiometric indication of titrations in aqueous solution in which STPB is used as the titrant and the species to be titrated has oleophilic properties. This results in ideal S-shaped titration curves.
This Bulletin describes the determination of active pharmaceutical ingredients in raw materials and formulations (tablets, powders, gels, creams, syrups, drops). These titrations are a valuable, environment-friendly alternative to other analytical methods.
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Pharmaceutical Industry > Pharmaceuticals
Methods
Titration > Potentiometric titration > Other potentiometric titrations
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